5SYJ
Crystal structure of the D141A variant of B. pseudomallei KatGin complex with isoniazid
Replaces: 4KWQSummary for 5SYJ
Entry DOI | 10.2210/pdb5syj/pdb |
Descriptor | Catalase-peroxidase, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, ... (8 entities in total) |
Functional Keywords | katg, catalase-peroxidase, oxidoreductase, isoniazid |
Biological source | Burkholderia pseudomallei (strain 1710b) |
Total number of polymer chains | 2 |
Total formula weight | 162019.70 |
Authors | Loewen, P.C. (deposition date: 2016-08-11, release date: 2016-09-21, Last modification date: 2023-10-04) |
Primary citation | Vidossich, P.,Loewen, P.C.,Carpena, X.,Fiorin, G.,Fita, I.,Rovira, C. Binding of the antitubercular pro-drug isoniazid in the heme access channel of catalase-peroxidase (KatG). A combined structural and metadynamics investigation. J Phys Chem B, 118:2924-2931, 2014 Cited by PubMed: 24568093DOI: 10.1021/jp4123425 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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