5SXS

Crystal structure of catalase-peroxidase KatG with isonicotinic acid hydrazide and AMP bound

Replaces:  3N3P

Summary for 5SXS

• Entry DOI: 10.2210/pdb5sxs/pdb
• Related: 5L02 5L05 5SW4 5SW5 5SW6 5SX0 5SX1 5SX2 5SX3 5SX6 5SX7 5SXQ 5SXR 5SXT 5SXX 5SYH 5SYI 5SYJ 5SYK 5SYL 5SYU 5SYV 5SYW 5SYX 5SYY
• Descriptor: Catalase-peroxidase, ADENOSINE MONOPHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE, ... (11 entities in total)
• Functional Keywords: catalase-peroxidase, tuberculosis, isoniazid, pro-drug activation, oxidoreductase
• Biological source: Burkholderia pseudomallei (strain 1710b)
• Total number of polymer chains: 2
• Total formula weight: 161462.47

Authors

Loewen, P.C. (deposition date: 2016-08-10, release date: 2016-09-07, Last modification date: 2023-10-04)

• Primary citation: Wiseman, B.,Carpena, X.,Feliz, M.,Donald, L.J.,Pons, M.,Fita, I.,Loewen, P.C.; Isonicotinic acid hydrazide conversion to Isonicotinyl-NAD by catalase-peroxidases.; J. Biol. Chem., 285:26662-26673, 2010; PubMed: 20554537; DOI: 10.1074/jbc.M110.139428

Experimental method

X-RAY DIFFRACTION (1.887 Å)