5SV6

Crystal structure of MxaJ from Methlophaga aminisulfidivorans MPT

5SV6 の概要

• エントリーDOI: 10.2210/pdb5sv6/pdb
• 分子名称: Extracellular solute-binding protein, family 3, BROMIDE ION (3 entities in total)
• 機能のキーワード: mxaj, methlophaga aminisulfidivorans, mdh, pbp, unknown function
• 由来する生物種: Methylophaga aminisulfidivorans MP
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 32919.78

構造登録者

Choi, J.M.,Lee, S.H. (登録日: 2016-08-04, 公開日: 2017-07-12, 最終更新日: 2024-11-20)

主引用文献

Choi, J.M.,Cao, T.P.,Kim, S.W.,Lee, K.H.,Lee, S.H.
MxaJ structure reveals a periplasmic binding protein-like architecture with unique secondary structural elements
Proteins, 85:1379-1386, 2017

PubMed Abstract: MxaJ is a component of type II methanol dehydrogenase (MDH) that mediates electron transfer during methanol oxidation in methanotrophic bacteria. However, little is known about how MxaJ structurally cooperates with MDH and Cytochrome c . Here, we report for the first time the crystal structure of MxaJ. MxaJ consists of eight α-helices and six β-strands, and resembles the "bi-lobate" folding architecture found in periplasmic binding proteins. Distinctive features of MxaJ include prominent loops and a β-strand around the hinge region supporting the ligand-binding cavity, which might provide a more favorable framework for interacting with proteins rather than small molecules. Proteins 2017; 85:1379-1386. © 2017 Wiley Periodicals, Inc.

PubMed: 28295618
DOI: 10.1002/prot.25283

実験手法

X-RAY DIFFRACTION (1.92 Å)