5SG3

Crystal Structure of human phosphodiesterase 10 in complex with N-[(E)-(4-bromo-3,5-dimethoxyphenyl)methylideneamino]-2-ethoxy-2-(4-morpholin-4-ylphenyl)acetamide

5SG3 の概要

• エントリーDOI: 10.2210/pdb5sg3/pdb
• Group deposition: To be published (G_1002229)
• 分子名称: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: phosphodiesterase, pde10, hydrolase, schizophrenia, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 160045.29

構造登録者

Joseph, C.,Benz, J.,Flohr, A.,Groebke-Zbinden, K.,Rudolph, M.G. (登録日: 2022-02-01, 公開日: 2022-10-12, 最終更新日: 2024-04-03)

• 主引用文献: Flohr, A.,Schlatter, D.,Kuhn, B.,Rudolph, M.G.; Crystal Structure of a human phosphodiesterase 10 complex; To be published,

実験手法

X-RAY DIFFRACTION (1.98 Å)