5S8O

XChem group deposition -- Crystal Structure of the second bromodomain of pleckstrin homology domain interacting protein (PHIP) in complex with N01460c (space group P212121)

5S8O の概要

• エントリーDOI: 10.2210/pdb5s8o/pdb
• Group deposition: XChem group deposition (G_1002187)
• 分子名称: PH-interacting protein, N-(4-chloro-2-methylphenyl)acetamide, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: sgc - diamond i04-1 fragment screening, bromodomain, phip, xchemexplorer, signaling protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 30948.57

構造登録者

Krojer, T.,Talon, R.,Fairhead, M.,Szykowska, A.,Burgess-Brown, N.A.,Brennan, P.E.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F. (登録日: 2020-12-17, 公開日: 2021-01-13, 最終更新日: 2024-03-06)

• 主引用文献: Krojer, T.,Talon, R.,Fairhead, M.,Szykowska, A.,Burgess-Brown, N.A.,Brennan, P.E.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F.; XChem group deposition; To Be Published,

実験手法

X-RAY DIFFRACTION (1.67 Å)