5RW0

PanDDA analysis group deposition -- Crystal Structure of DHTKD1 in complex with Z2444997446

Summary for 5RW0

• Entry DOI: 10.2210/pdb5rw0/pdb
• Group deposition: PanDDA analysis group deposition (G_1002178)
• Descriptor: Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial, 1-{(2S,4S)-4-fluoro-1-[(2-methyl-1,3-thiazol-4-yl)methyl]pyrrolidin-2-yl}methanamine, THIAMINE DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 203922.34

Authors

Bezerra, G.A.,Foster, W.R.,Bailey, H.J.,Shrestha, L.,Krojer, T.,Brandao-Neto, J.,Douangamath, A.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Yue, W.W. (deposition date: 2020-10-27, release date: 2020-11-25, Last modification date: 2024-03-06)

• Primary citation: Bezerra, G.A.,Foster, W.R.,Bailey, H.J.,Shrestha, L.,Krojer, T.,Brandao-Neto, J.,Douangamath, A.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Yue, W.W.; PanDDA analysis group deposition; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.673 Å)