5RGH
PanDDA analysis group deposition SARS-CoV-2 main protease fragment screen -- Crystal Structure of SARS-CoV-2 main protease in complex with Z1619978933 (Mpro-x0395)
5RGH の概要
エントリーDOI | 10.2210/pdb5rgh/pdb |
Group deposition | PanDDA analysis group deposition SARS-CoV-2 main protease fragment screen (G_1002153) |
分子名称 | 3C-like proteinase, DIMETHYL SULFOXIDE, 5-fluoro-1-[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]-1,2,3,6-tetrahydropyridine, ... (4 entities in total) |
機能のキーワード | sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
由来する生物種 | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 34351.35 |
構造登録者 | Fearon, D.,Owen, C.D.,Douangamath, A.,Lukacik, P.,Powell, A.J.,Strain-Damerell, C.M.,Resnick, E.,Krojer, T.,Gehrtz, P.,Wild, C.,Aimon, A.,Brandao-Neto, J.,Carbery, A.,Dunnett, L.,Skyner, R.,Snee, M.,London, N.,Walsh, M.A.,von Delft, F. (登録日: 2020-04-07, 公開日: 2020-04-15, 最終更新日: 2024-03-06) |
主引用文献 | Douangamath, A.,Fearon, D.,Gehrtz, P.,Krojer, T.,Lukacik, P.,Owen, C.D.,Resnick, E.,Strain-Damerell, C.,Aimon, A.,Abranyi-Balogh, P.,Brandao-Neto, J.,Carbery, A.,Davison, G.,Dias, A.,Downes, T.D.,Dunnett, L.,Fairhead, M.,Firth, J.D.,Jones, S.P.,Keeley, A.,Keseru, G.M.,Klein, H.F.,Martin, M.P.,Noble, M.E.M.,O'Brien, P.,Powell, A.,Reddi, R.N.,Skyner, R.,Snee, M.,Waring, M.J.,Wild, C.,London, N.,von Delft, F.,Walsh, M.A. Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease. Nat Commun, 11:5047-5047, 2020 Cited by PubMed: 33028810DOI: 10.1038/s41467-020-18709-w 主引用文献が同じPDBエントリー |
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