5RGE

Crystal Structure of Kemp Eliminase HG3.17 with bound transition state analog, 277K

5RGE の概要

• エントリーDOI: 10.2210/pdb5rge/pdb
• Group deposition: Crystal structures of HG-series of Kemp Eliminases at Room-temperature (G_1002148)
• 分子名称: Kemp Eliminase HG3, 6-NITROBENZOTRIAZOLE (3 entities in total)
• 機能のキーワード: hydrolase
• 由来する生物種: Thermoascus aurantiacus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34639.97

構造登録者

Broom, A.,Rakotoharisoa, R.V.,Thompson, M.C.,Fraser, J.S.,Chica, R.A. (登録日: 2020-03-19, 公開日: 2020-07-22, 最終更新日: 2024-03-06)

• 主引用文献: Broom, A.,Rakotoharisoa, R.V.,Thompson, M.C.,Zarifi, N.,Nguyen, E.,Mukhametzhanov, N.,Liu, L.,Fraser, J.S.,Chica, R.A.; Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico.; Nat Commun, 11:4808-4808, 2020; PubMed: 32968058; DOI: 10.1038/s41467-020-18619-x

実験手法

X-RAY DIFFRACTION (1.77 Å)