5QXS

PanDDA analysis group deposition -- Crystal Structure of ATAD2 in complex with DF852

5QXS の概要

• エントリーDOI: 10.2210/pdb5qxs/pdb
• Group deposition: PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening (G_1002118)
• 分子名称: ATPase family AAA domain-containing protein 2, (4aR,7aR,9R)-3,4,7,7a,8,9-hexahydro-4a,9-epoxypyrrolo[3',4':4,5]cyclohepta[1,2-d]imidazole-6(5H)-carbaldehyde, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16267.30

構造登録者

Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F. (登録日: 2020-03-09, 公開日: 2020-04-08, 最終更新日: 2024-03-06)

• 主引用文献: Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F.; PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening; To Be Published,

実験手法

X-RAY DIFFRACTION (1.62 Å)