5QXK
PanDDA analysis group deposition -- Crystal Structure of ATAD2 in complex with PC581
Summary for 5QXK
Entry DOI | 10.2210/pdb5qxk/pdb |
Group deposition | PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening (G_1002118) |
Descriptor | ATPase family AAA domain-containing protein 2, (3aS,8S,9aS)-2-acetyl-10-methyl-2,3,6,8,9,9a-hexahydro-3a,8-epiminocyclohepta[1,2-c:4,5-c']dipyrrol-4(1H)-one, SULFATE ION, ... (5 entities in total) |
Functional Keywords | sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 16212.26 |
Authors | Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F. (deposition date: 2020-02-11, release date: 2020-04-08, Last modification date: 2024-03-06) |
Primary citation | Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F. PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.72 Å) |
Structure validation
Download full validation report