5QT3

Ground state model of human erythroid-specific 5'-aminolevulinate synthase, ALAS2 - SGC Diamond Xchem fragment screening

Summary for 5QT3

• Entry DOI: 10.2210/pdb5qt3/pdb
• Group deposition: PanDDA analysis group deposition of ground-state model (G_1002088)
• Descriptor: 5-aminolevulinate synthase, erythroid-specific, mitochondrial, PYRIDOXAL-5'-PHOSPHATE (3 entities in total)
• Functional Keywords: sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 104995.39

Authors

Bezerra, G.A.,Foster, W.,Bailey, H.,Shrestha, L.,Krojer, T.,Talon, R.,Brandao-Neto, J.,Douangamath, A.,Nicola, B.B.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Brennan, P.E.,Yue, W.W. (deposition date: 2019-06-28, release date: 2019-08-07, Last modification date: 2024-03-06)

• Primary citation: Bezerra, G.A.,Foster, W.,Bailey, H.,Shrestha, L.,Krojer, T.,Talon, R.,Brandao-Neto, J.,Douangamath, A.,Nicola, B.B.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Brennan, P.E.,Yue, W.W.; PanDDA analysis group deposition of ground-state model; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)