5QR7

PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z57299529

Summary for 5QR7

Entry DOI	10.2210/pdb5qr7/pdb
Group deposition	PanDDA analysis group deposition (G_1002078)
Descriptor	5-aminolevulinate synthase, erythroid-specific, mitochondrial, PYRIDOXAL-5'-PHOSPHATE, ~{N}-(2-phenylethyl)-1~{H}-benzimidazol-2-amine, ... (4 entities in total)
Functional Keywords	sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	105469.99
Authors	Bezerra, G.A.,Foster, W.,Bailey, H.,Shrestha, L.,Krojer, T.,Talon, R.,Brandao-Neto, J.,Douangamath, A.,Nicola, B.B.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Brennan, P.E.,Yue, W.W. (deposition date: 2019-05-22, release date: 2019-08-07, Last modification date: 2024-03-06)
Primary citation	Bezerra, G.A.,Foster, W.,Bailey, H.,Shrestha, L.,Krojer, T.,Talon, R.,Brandao-Neto, J.,Douangamath, A.,Nicola, B.B.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Brennan, P.E.,Yue, W.W. PanDDA analysis group deposition To Be Published,
Experimental method	X-RAY DIFFRACTION (1.74 Å)

Structure validation