5QIT

Covalent fragment group deposition -- Crystal Structure of OUTB2 in complex with PCM-0102821

5QIT の概要

• エントリーDOI: 10.2210/pdb5qit/pdb
• Group deposition: Covalent fragment group deposition (G_1002053)
• 分子名称: Ubiquitin thioesterase OTUB2, N-[(E)-(3-methylphenyl)methylidene]acetamide, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: sgc - diamond i04-1 fragment screening, xchemexplorer, protease otub2, deubiquitinating enzyme otub2, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26815.53

構造登録者

Sethi, R.,Douangamath, A.,Resnick, E.,Bradley, A.R.,Collins, P.,Brandao-Neto, J.,Talon, R.,Krojer, T.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,London, N.,von Delft, F. (登録日: 2018-08-10, 公開日: 2019-12-18)

• 主引用文献: Sethi, R.,Douangamath, A.,Resnick, E.,Bradley, A.R.,Collins, P.,Brandao-Neto, J.,Talon, R.,Krojer, T.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,London, N.,von Delft, F.; Covalent fragment group deposition; To Be Published,

実験手法

X-RAY DIFFRACTION (1.46 Å)