5QCJ
Crystal structure of human Cathepsin-S with bound ligand
Summary for 5QCJ
Entry DOI | 10.2210/pdb5qcj/pdb |
Group deposition | Ligand binding to Cathepsin S (G_1002040) |
Descriptor | Cathepsin S, 5-hydroxy-3-{1-[(2S)-2-hydroxy-3-{5-(methylsulfonyl)-3-[4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl}propyl]piperidin-4-yl}-1H-pyrrolo[3,2-c]pyridin-5-ium, SULFATE ION, ... (4 entities in total) |
Functional Keywords | d3r, cathepsin s, ligand docking, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 75696.64 |
Authors | Bembenek, S.D.,Ameriks, M.K.,Mirzadegan, T.,Yang, H.,Shao, C.,Burley, S.K. (deposition date: 2017-08-04, release date: 2017-12-20, Last modification date: 2021-11-17) |
Primary citation | Bembenek, S.D.,Ameriks, M.K.,Mirzadegan, T.,Yang, H.,Shao, C.,Burley, S.K. Crystal structure of human Cathepsin-S with bound ligand To be published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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