5QBU
Crystal structure of human Cathepsin-S with bound ligand
Summary for 5QBU
Entry DOI | 10.2210/pdb5qbu/pdb |
Group deposition | Ligand binding to Cathepsin S (G_1002040) |
Descriptor | Cathepsin S, 1-[1-(3-{5-(1H-imidazole-5-carbonyl)-3-[4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl}propyl)piperidin-4-yl]-3-methyl-1,3-dihydro-2H-benzimidazol-2-one (3 entities in total) |
Functional Keywords | d3r, cathepsin s, ligand docking, hydrolase |
Biological source | Homo sapiens |
Total number of polymer chains | 2 |
Total formula weight | 50298.30 |
Authors | Bembenek, S.D.,Ameriks, M.K.,Mirzadegan, T.,Yang, H.,Shao, C.,Burley, S.K. (deposition date: 2017-08-04, release date: 2017-12-20, Last modification date: 2021-11-17) |
Primary citation | Bembenek, S.D.,Ameriks, M.K.,Mirzadegan, T.,Yang, H.,Shao, C.,Burley, S.K. Crystal structure of human Cathepsin-S with bound ligand To be published, |
Experimental method | X-RAY DIFFRACTION (2.78 Å) |
Structure validation
Download full validation report