5PZ3
PanDDA analysis group deposition -- Crystal Structure of SP100 after initial refinement with no ligand modelled (structure 99)
Summary for 5PZ3
Entry DOI | 10.2210/pdb5pz3/pdb |
Group deposition | PanDDA analysis group deposition of models of ground state datasets (G_1002025) |
Descriptor | Nuclear autoantigen Sp-100, ZINC ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (5 entities in total) |
Functional Keywords | pandda, sgc - diamond i04-1 fragment screening, bromodomain, epigenetics, xchemexplorer, transcription |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus. Isoform Sp100-C: Nucleus : P23497 |
Total number of polymer chains | 2 |
Total formula weight | 43643.55 |
Authors | Pearce, N.M.,Krojer, T.,Talon, R.,Bradley, A.R.,Fairhead, M.,Sethi, R.,Wright, N.,MacLean, E.,Collins, P.,Brandao-Neto, J.,Douangamath, A.,Renjie, Z.,Dias, A.,Ng, J.,Brennan, P.E.,Cox, O.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,von Delft, F. (deposition date: 2017-02-08, release date: 2017-03-22, Last modification date: 2024-03-06) |
Primary citation | Pearce, N.M.,Krojer, T.,Bradley, A.R.,Collins, P.,Nowak, R.P.,Talon, R.,Marsden, B.D.,Kelm, S.,Shi, J.,Deane, C.M.,von Delft, F. A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8:15123-15123, 2017 Cited by PubMed: 28436492DOI: 10.1038/ncomms15123 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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