5PBX

PanDDA analysis group deposition -- Crystal Structure of BAZ2B after initial refinement with no ligand modelled (structure 18)

Summary for 5PBX

Group depositionPanDDA analysis group deposition of models of ground state datasets (G_1002019)
DescriptorBromodomain adjacent to zinc finger domain protein 2B, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywordspandda, sgc - diamond i04-1 fragment screening, bromodomain, epigenetics, dna binding protein
Biological sourceHomo sapiens (Human)
Cellular locationNucleus  Q9UIF8
Total number of polymer chains1
Total molecular weight16152.39
Authors
Primary citation
Pearce, N.M.,Krojer, T.,Bradley, A.R.,Collins, P.,Nowak, R.P.,Talon, R.,Marsden, B.D.,Kelm, S.,Shi, J.,Deane, C.M.,von Delft, F.
A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.
Nat Commun, 8:15123-15123, 2017
PubMed: 28436492 (PDB entries with the same primary citation)
DOI: 10.1038/ncomms15123
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.65 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.221401.0%1.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution