5PB7

PanDDA analysis group deposition -- Crystal Structure of BAZ2B in complex with N09440a

5PB7 の概要

• エントリーDOI: 10.2210/pdb5pb7/pdb
• Group deposition: PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) (G_1002018)
• 分子名称: Bromodomain adjacent to zinc finger domain protein 2B, 1,2-ETHANEDIOL, 1~{H}-indazol-5-amine, ... (4 entities in total)
• 機能のキーワード: pandda, sgc - diamond i04-1 fragment screening, bromodomain, epigenetics, dna binding protein
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus : Q9UIF8
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16409.68

構造登録者

Pearce, N.M.,Krojer, T.,Talon, R.,Bradley, A.R.,Fairhead, M.,Sethi, R.,Wright, N.,MacLean, E.,Collins, P.,Brandao-Neto, J.,Douangamath, A.,Renjie, Z.,Dias, A.,Vollmar, M.,Ng, J.,Brennan, P.E.,Cox, O.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,von Delft, F. (登録日: 2017-02-03, 公開日: 2017-03-15, 最終更新日: 2024-03-06)

• 主引用文献: Pearce, N.M.,Krojer, T.,Bradley, A.R.,Collins, P.,Nowak, R.P.,Talon, R.,Marsden, B.D.,Kelm, S.,Shi, J.,Deane, C.M.,von Delft, F.; A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.; Nat Commun, 8:15123-15123, 2017; PubMed: 28436492; DOI: 10.1038/ncomms15123

実験手法

X-RAY DIFFRACTION (1.655 Å)