5PB5

human factor VIIa in complex with 1-[[3-[5-hydroxy-4-(7H-pyrrolo[2,3-d]pyrimidin-6-yl)pyrazol-1-yl]phenyl]methyl]-3-phenylurea at 1.84A

Summary for 5PB5

• Entry DOI: 10.2210/pdb5pb5/pdb
• Group deposition: Crystal Structure of a Factor VIIa complex (G_1002016)
• Descriptor: Coagulation factor VII light chain, Coagulation factor VII heavy chain, GLYCEROL, ... (8 entities in total)
• Functional Keywords: glycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human); More
• Cellular location: Secreted: P08709 P08709
• Total number of polymer chains: 2
• Total formula weight: 35873.36

Authors

Stihle, M.,Mayweg, A.,Roever, S.,Rudolph, M.G. (deposition date: 2016-11-16, release date: 2017-06-21, Last modification date: 2024-11-13)

• Primary citation: Mayweg, A.,Roever, S.,Rudolph, M.G.; Crystal Structure of a Factor VIIa complex; To be published,

Experimental method

X-RAY DIFFRACTION (1.84 Å)