5P9N
humanized rat COMT in complex with 5-(4-fluorophenyl)-2,3-dihydroxy-N-[[3-[hydroxy-(1-methylindazol-5-yl)methyl]phenyl]methyl]benzamide at 1.17A
Summary for 5P9N
Entry DOI | 10.2210/pdb5p9n/pdb |
Group deposition | Crystal Structure of COMT complex (G_1002014) |
Descriptor | Catechol O-methyltransferase, MAGNESIUM ION, CHLORIDE ION, ... (9 entities in total) |
Functional Keywords | methyltransferase, neurotransmitter degradation, transferase |
Biological source | Rattus norvegicus (Rat) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734 |
Total number of polymer chains | 1 |
Total formula weight | 26240.16 |
Authors | Ehler, A.,Jakob-Roetne, R.,Rudolph, M.G. (deposition date: 2016-10-19, release date: 2017-11-22, Last modification date: 2024-04-03) |
Primary citation | Lerner, C.,Jakob-Roetne, R.,Groebke-Zbinden, K.,Buettelmann, B.,Rudolph, M.G. Crystal Structure of a COMT complex To be published, |
Experimental method | X-RAY DIFFRACTION (1.17 Å) |
Structure validation
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