5P9D

rat catechol O-methyltransferase in complex with 5-(4-fluorophenyl)-2,3-dihydroxy-N-(5-imidazol-1-ylpentyl)benzamide at 1.42A

Summary for 5P9D

Entry DOI	10.2210/pdb5p9d/pdb
Group deposition	Crystal Structure of COMT complex (G_1002010)
Descriptor	Catechol O-methyltransferase, MAGNESIUM ION, 5-(4-fluorophenyl)-2,3-dihydroxy-N-(5-imidazol-1-ylpentyl)benzamide, ... (7 entities in total)
Functional Keywords	methyltransferase, neurotransmitter degradation, transferase
Biological source	Rattus norvegicus (Rat)
Cellular location	Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734
Total number of polymer chains	1
Total formula weight	25467.52
Authors	Ehler, A.,Lerner, C.,Rudolph, M.G. (deposition date: 2016-08-30, release date: 2017-08-30, Last modification date: 2024-04-03)
Primary citation	Lerner, C.,Rudolph, M.G. Crystal Structure of a COMT complex To be published,
Experimental method	X-RAY DIFFRACTION (1.42 Å)

Structure validation