5P99
rat catechol O-methyltransferase in complex with N-[2-[2-(3,4-dihydroxyphenyl)-2-oxoethyl]sulfanylethyl]-5-(4-fluorophenyl)-2,3-dihydroxybenzamide at 1.20A
Summary for 5P99
Entry DOI | 10.2210/pdb5p99/pdb |
Group deposition | Crystal Structure of COMT complex (G_1002010) |
Descriptor | Catechol O-methyltransferase, MAGNESIUM ION, CHLORIDE ION, ... (8 entities in total) |
Functional Keywords | methyltransferase, neurotransmitter degradation, transferase |
Biological source | Rattus norvegicus (Rat) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734 |
Total number of polymer chains | 1 |
Total formula weight | 25780.67 |
Authors | Ehler, A.,Lerner, C.,Rudolph, M.G. (deposition date: 2016-08-30, release date: 2017-08-30, Last modification date: 2024-04-03) |
Primary citation | Lerner, C.,Rudolph, M.G. Crystal Structure of a COMT complex To be published, |
Experimental method |
Structure validation
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