5P99

rat catechol O-methyltransferase in complex with N-[2-[2-(3,4-dihydroxyphenyl)-2-oxoethyl]sulfanylethyl]-5-(4-fluorophenyl)-2,3-dihydroxybenzamide at 1.20A

5P99 の概要

• エントリーDOI: 10.2210/pdb5p99/pdb
• Group deposition: Crystal Structure of COMT complex (G_1002010)
• 分子名称: Catechol O-methyltransferase, MAGNESIUM ION, CHLORIDE ION, ... (8 entities in total)
• 機能のキーワード: methyltransferase, neurotransmitter degradation, transferase
• 由来する生物種: Rattus norvegicus (Rat)
• 細胞内の位置: Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25780.67

構造登録者

Ehler, A.,Lerner, C.,Rudolph, M.G. (登録日: 2016-08-30, 公開日: 2017-08-30, 最終更新日: 2024-04-03)

• 主引用文献: Lerner, C.,Rudolph, M.G.; Crystal Structure of a COMT complex; To be published,

実験手法

X-RAY DIFFRACTION (1.2 Å)