5OWY

Glycogen Phosphorylase in complex with KS252

5OWY の概要

• エントリーDOI: 10.2210/pdb5owy/pdb
• 分子名称: Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, 4-[5-[(2~{S},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-4~{H}-1,2,4-triazol-3-yl]benzoic acid, ... (5 entities in total)
• 機能のキーワード: transferase
• 由来する生物種: Oryctolagus cuniculus (Rabbit)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 98369.06

構造登録者

Kyriakis, E.,Stravodimos, G.,Kantsadi, A.,Chatzileontiadou, D.,Leonidas, D. (登録日: 2017-09-05, 公開日: 2018-02-28)

• 主引用文献: Kyriakis, E.,Solovou, T.G.A.,Kun, S.,Czifrak, K.,Szocs, B.,Juhasz, L.,Bokor, E.,Stravodimos, G.A.,Kantsadi, A.L.,Chatzileontiadou, D.S.M.,Skamnaki, V.T.,Somsak, L.,Leonidas, D.D.; Probing the beta-pocket of the active site of human liver glycogen phosphorylase with 3-(C-beta-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.; Bioorg. Chem., 77:485-493, 2018; PubMed: 29454281; DOI: 10.1016/j.bioorg.2018.02.008

実験手法

X-RAY DIFFRACTION (1.9 Å)