5OM4

Structure of the A2A-StaR2-bRIL562-Compound 4e complex at 1.86A obtained from in meso soaking experiments (24 hour soak).

Summary for 5OM4

Entry DOI	10.2210/pdb5om4/pdb
Descriptor	Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, 4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol, SODIUM ION, ... (7 entities in total)
Functional Keywords	g-protein coupled receptor, adenosine 2a receptor, 7 tm integral membrane protein, thermostabilizing mutations, membrane protein
Biological source	Homo sapiens (Human) More
Cellular location	Cell membrane; Multi-pass membrane protein: P29274
Total number of polymer chains	1
Total formula weight	58377.47
Authors	Rucktooa, P.,Cheng, R.K.Y.,Segala, E.,Geng, T.,Errey, J.C.,Brown, G.A.,Cooke, R.,Marshall, F.H.,Dore, A.S. (deposition date: 2017-07-28, release date: 2018-01-17, Last modification date: 2024-01-17)
Primary citation	Rucktooa, P.,Cheng, R.K.Y.,Segala, E.,Geng, T.,Errey, J.C.,Brown, G.A.,Cooke, R.M.,Marshall, F.H.,Dore, A.S. Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals. Sci Rep, 8:41-41, 2018 Cited by PubMed: 29311713 DOI: 10.1038/s41598-017-18570-w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation