5OLV

Structure of the A2A-StaR2-bRIL562-LUAA47070 complex at 2.0A obtained from in meso soaking experiments.

5OLV の概要

• エントリーDOI: 10.2210/pdb5olv/pdb
• 分子名称: Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, 4-(3,3-dimethylbutanoylamino)-3,5-bis(fluoranyl)-~{N}-(1,3-thiazol-2-yl)benzamide, SODIUM ION, ... (7 entities in total)
• 機能のキーワード: g-protein coupled receptor, adenosine 2a receptor, 7 tm integral membrane protein, thermostabilizing mutations, membrane protein
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cell membrane; Multi-pass membrane protein: P29274
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 57228.21

構造登録者

Rucktooa, P.,Cheng, R.K.Y.,Segala, E.,Geng, T.,Errey, J.C.,Brown, G.A.,Cooke, R.,Marshall, F.H.,Dore, A.S. (登録日: 2017-07-28, 公開日: 2018-01-17, 最終更新日: 2024-01-17)

• 主引用文献: Rucktooa, P.,Cheng, R.K.Y.,Segala, E.,Geng, T.,Errey, J.C.,Brown, G.A.,Cooke, R.M.,Marshall, F.H.,Dore, A.S.; Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals.; Sci Rep, 8:41-41, 2018; PubMed: 29311713; DOI: 10.1038/s41598-017-18570-w

実験手法

X-RAY DIFFRACTION (1.998 Å)