5OLG

Structure of the A2A-StaR2-bRIL562-ZM241385 complex at 1.86A obtained from in meso soaking experiments.

Summary for 5OLG

• Entry DOI: 10.2210/pdb5olg/pdb
• Descriptor: Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, CHOLESTEROL, ... (9 entities in total)
• Functional Keywords: g-protein coupled receptor, adenosine 2a receptor, 7 tm integral membrane protein, thermostabilizing mutations, membrane proteins, membrane protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Cell membrane; Multi-pass membrane protein: P29274
• Total number of polymer chains: 1
• Total formula weight: 56270.68

Authors

Rucktooa, P.,Cheng, R.K.Y.,Segala, E.,Geng, T.,Errey, J.C.,Brown, G.A.,Cooke, R.,Marshall, F.H.,Dore, A.S. (deposition date: 2017-07-27, release date: 2018-01-17, Last modification date: 2024-02-07)

• Primary citation: Rucktooa, P.,Cheng, R.K.Y.,Segala, E.,Geng, T.,Errey, J.C.,Brown, G.A.,Cooke, R.M.,Marshall, F.H.,Dore, A.S.; Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals.; Sci Rep, 8:41-41, 2018; PubMed: 29311713; DOI: 10.1038/s41598-017-18570-w

Experimental method

X-RAY DIFFRACTION (1.87 Å)