5OLG

Structure of the A2A-StaR2-bRIL562-ZM241385 complex at 1.86A obtained from in meso soaking experiments.

5OLG の概要

• エントリーDOI: 10.2210/pdb5olg/pdb
• 分子名称: Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, CHOLESTEROL, ... (9 entities in total)
• 機能のキーワード: g-protein coupled receptor, adenosine 2a receptor, 7 tm integral membrane protein, thermostabilizing mutations, membrane proteins, membrane protein
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cell membrane; Multi-pass membrane protein: P29274
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 56270.68

構造登録者

Rucktooa, P.,Cheng, R.K.Y.,Segala, E.,Geng, T.,Errey, J.C.,Brown, G.A.,Cooke, R.,Marshall, F.H.,Dore, A.S. (登録日: 2017-07-27, 公開日: 2018-01-17, 最終更新日: 2024-02-07)

• 主引用文献: Rucktooa, P.,Cheng, R.K.Y.,Segala, E.,Geng, T.,Errey, J.C.,Brown, G.A.,Cooke, R.M.,Marshall, F.H.,Dore, A.S.; Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals.; Sci Rep, 8:41-41, 2018; PubMed: 29311713; DOI: 10.1038/s41598-017-18570-w

実験手法

X-RAY DIFFRACTION (1.87 Å)