5OIZ
Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae in complex with oxacillin
Summary for 5OIZ
Entry DOI | 10.2210/pdb5oiz/pdb |
Descriptor | Penicillin-binding protein 2X, (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid (3 entities in total) |
Functional Keywords | penicillin, b-lactam, cell-wall, transpeptidase, antibiotic |
Biological source | Streptococcus pneumoniae (strain ATCC BAA-255 / R6) |
Total number of polymer chains | 1 |
Total formula weight | 77211.42 |
Authors | Bernardo-Garcia, N.,Hermoso, J.A. (deposition date: 2017-07-20, release date: 2018-05-30, Last modification date: 2024-01-17) |
Primary citation | Bernardo-Garcia, N.,Mahasenan, K.V.,Batuecas, M.T.,Lee, M.,Hesek, D.,Petrackova, D.,Doubravova, L.,Branny, P.,Mobashery, S.,Hermoso, J.A. Allostery, Recognition of Nascent Peptidoglycan, and Cross-linking of the Cell Wall by the Essential Penicillin-Binding Protein 2x of Streptococcus pneumoniae. ACS Chem. Biol., 13:694-702, 2018 Cited by PubMed: 29357220DOI: 10.1021/acschembio.7b00817 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report