5OG0
Crystal structure of human Alanine:Glyoxylate Aminotransferase major allele (AGT-Ma) at 2.5 Angstrom; internal aldimine with PLP in the active site
Summary for 5OG0
Entry DOI | 10.2210/pdb5og0/pdb |
Related | 5F9S |
Descriptor | Serine--pyruvate aminotransferase, PYRIDOXAL-5'-PHOSPHATE (3 entities in total) |
Functional Keywords | aminotransferase, detoxification, liver, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Peroxisome : P21549 |
Total number of polymer chains | 1 |
Total formula weight | 43309.98 |
Authors | Giardina, G.,Cutruzzola, F.,Borri Voltattorni, C.,Cellini, B.,Montioli, R. (deposition date: 2017-07-11, release date: 2017-09-27, Last modification date: 2024-01-17) |
Primary citation | Giardina, G.,Paiardini, A.,Montioli, R.,Cellini, B.,Voltattorni, C.B.,Cutruzzola, F. Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis. Sci Rep, 7:11704-11704, 2017 Cited by PubMed: 28916765DOI: 10.1038/s41598-017-11948-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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