5OG0

Crystal structure of human Alanine:Glyoxylate Aminotransferase major allele (AGT-Ma) at 2.5 Angstrom; internal aldimine with PLP in the active site

5OG0 の概要

• エントリーDOI: 10.2210/pdb5og0/pdb
• 関連するPDBエントリー: 5F9S
• 分子名称: Serine--pyruvate aminotransferase, PYRIDOXAL-5'-PHOSPHATE (3 entities in total)
• 機能のキーワード: aminotransferase, detoxification, liver, transferase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Peroxisome : P21549
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43309.98

構造登録者

Giardina, G.,Cutruzzola, F.,Borri Voltattorni, C.,Cellini, B.,Montioli, R. (登録日: 2017-07-11, 公開日: 2017-09-27, 最終更新日: 2024-01-17)

• 主引用文献: Giardina, G.,Paiardini, A.,Montioli, R.,Cellini, B.,Voltattorni, C.B.,Cutruzzola, F.; Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis.; Sci Rep, 7:11704-11704, 2017; PubMed: 28916765; DOI: 10.1038/s41598-017-11948-w

実験手法

X-RAY DIFFRACTION (2.5 Å)