5OCX

Crystal structure of ACPA E4 in complex with CII-C-13-CIT

5OCX の概要

• エントリーDOI: 10.2210/pdb5ocx/pdb
• 分子名称: Fab fragment anti-citrullinated protein antibody E4 - light chain, Fab fragment of anti-citrullinated protein antibody E4 - heavy chain, CII-C-13-CIT, ... (5 entities in total)
• 機能のキーワード: anti-citrullinated protein antibody fab fragment, collagen type ii epitope immune system, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 48887.31

構造登録者

Dobritzsch, D.,Ge, C.,Holmdahl, R. (登録日: 2017-07-04, 公開日: 2018-07-04, 最終更新日: 2024-01-17)

• 主引用文献: Ge, C.,Xu, B.,Liang, B.,Lonnblom, E.,Lundstrom, S.L.,Zubarev, R.A.,Ayoglu, B.,Nilsson, P.,Skogh, T.,Kastbom, A.,Malmstrom, V.,Klareskog, L.,Toes, R.E.M.,Rispens, T.,Dobritzsch, D.,Holmdahl, R.; Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.; Arthritis Rheumatol, 71:210-221, 2019; PubMed: 30152126; DOI: 10.1002/art.40698

実験手法

X-RAY DIFFRACTION (1.75 Å)