5OCE

THE MOLECULAR MECHANISM OF SUBSTRATE RECOGNITION AND CATALYSIS OF THE MEMBRANE ACYLTRANSFERASE PatA -- Complex of PatA with palmitate, mannose, and palmitoyl-6-mannose

5OCE の概要

• エントリーDOI: 10.2210/pdb5oce/pdb
• 分子名称: Phosphatidylinositol mannoside acyltransferase, PALMITIC ACID, beta-D-mannopyranose, ... (5 entities in total)
• 機能のキーワード: acyltransferase, glycolipid biosynthesis, transferase
• 由来する生物種: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
• 細胞内の位置: Cell membrane ; Single-pass membrane protein : A0QWG5
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 136056.52

構造登録者

Albesa-Jove, D.,Tersa, M.,Guerin, M.E. (登録日: 2017-06-30, 公開日: 2017-12-27, 最終更新日: 2024-01-17)

• 主引用文献: Tersa, M.,Raich, L.,Albesa-Jove, D.,Trastoy, B.,Prandi, J.,Gilleron, M.,Rovira, C.,Guerin, M.E.; The Molecular Mechanism of Substrate Recognition and Catalysis of the Membrane Acyltransferase PatA from Mycobacteria.; ACS Chem. Biol., 13:131-140, 2018; PubMed: 29185694; DOI: 10.1021/acschembio.7b00578

実験手法

X-RAY DIFFRACTION (2.41 Å)