5OAY

M. tuberculosis [4Fe-4S] protein WhiB1 is a four-helix bundle that forms a NO-sensitive complex with sigmaA and regulates the major virulence factor ESX-1

Summary for 5OAY

• Entry DOI: 10.2210/pdb5oay/pdb
• NMR Information: BMRB: 34153
• Descriptor: Transcriptional regulator WhiB1, IRON/SULFUR CLUSTER (2 entities in total)
• Functional Keywords: nitric oxide, sigmaa, iron-sulfur, tuberculosis, wbl protein, signaling protein
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• Cellular location: Cytoplasm : P9WF43
• Total number of polymer chains: 1
• Total formula weight: 10735.32

Authors

Williamson, M.P.,Green, J.,Hounslow, A.M. (deposition date: 2017-06-25, release date: 2018-01-03, Last modification date: 2024-05-15)

• Primary citation: Kudhair, B.K.,Hounslow, A.M.,Rolfe, M.D.,Crack, J.C.,Hunt, D.M.,Buxton, R.S.,Smith, L.J.,Le Brun, N.E.,Williamson, M.P.,Green, J.; Structure of a Wbl protein and implications for NO sensing by M. tuberculosis.; Nat Commun, 8:2280-2280, 2017; PubMed: 29273788; DOI: 10.1038/s41467-017-02418-y

Experimental method

SOLUTION NMR