5OA0
Crystal structure of mutant AChBP in complex with strychnine (T53F, Q74R, Y110A, I135S, W164F)
Summary for 5OA0
Entry DOI | 10.2210/pdb5oa0/pdb |
Descriptor | Soluble acetylcholine receptor, STRYCHNINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | receptor, acetylcholine binding, signaling protein |
Biological source | Aplysia californica (California sea hare) |
Total number of polymer chains | 5 |
Total formula weight | 144082.67 |
Authors | Dawson, A.,Hunter, W.N.,de Souza, J.O.,Trumper, P. (deposition date: 2017-06-20, release date: 2018-08-01, Last modification date: 2024-01-17) |
Primary citation | Dawson, A.,Trumper, P.,de Souza, J.O.,Parker, H.,Jones, M.J.,Hales, T.G.,Hunter, W.N. Engineering a surrogate human heteromeric alpha / beta glycine receptor orthosteric site exploiting the structural homology and stability of acetylcholine-binding protein. Iucrj, 6:1014-1023, 2019 Cited by PubMed: 31709057DOI: 10.1107/S205225251901114X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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