5OA0

Crystal structure of mutant AChBP in complex with strychnine (T53F, Q74R, Y110A, I135S, W164F)

Summary for 5OA0

Entry DOI	10.2210/pdb5oa0/pdb
Descriptor	Soluble acetylcholine receptor, STRYCHNINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	receptor, acetylcholine binding, signaling protein
Biological source	Aplysia californica (California sea hare)
Total number of polymer chains	5
Total formula weight	144082.67
Authors	Dawson, A.,Hunter, W.N.,de Souza, J.O.,Trumper, P. (deposition date: 2017-06-20, release date: 2018-08-01, Last modification date: 2024-01-17)
Primary citation	Dawson, A.,Trumper, P.,de Souza, J.O.,Parker, H.,Jones, M.J.,Hales, T.G.,Hunter, W.N. Engineering a surrogate human heteromeric alpha / beta glycine receptor orthosteric site exploiting the structural homology and stability of acetylcholine-binding protein. Iucrj, 6:1014-1023, 2019 Cited by PubMed: 31709057 DOI: 10.1107/S205225251901114X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation