5O7K

Crystal structure of a single chain monellin mutant (Y65R) pH 2.0

5O7K の概要

• エントリーDOI: 10.2210/pdb5o7k/pdb
• 関連するPDBエントリー: 5LC6 5LC7
• 分子名称: Monellin chain B,Monellin chain A, SULFATE ION (3 entities in total)
• 機能のキーワード: plant protein, sweet protein, sweetener
• 由来する生物種: Dioscoreophyllum cumminsii (Serendipity berry); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22948.00

構造登録者

Pica, A.,Merlino, A. (登録日: 2017-06-09, 公開日: 2018-01-10, 最終更新日: 2024-01-17)

主引用文献

Pica, A.,Leone, S.,Di Girolamo, R.,Donnarumma, F.,Emendato, A.,Rega, M.F.,Merlino, A.,Picone, D.
pH driven fibrillar aggregation of the super-sweet protein Y65R-MNEI: A step-by-step structural analysis.
Biochim. Biophys. Acta, 1862:808-815, 2017

PubMed Abstract: MNEI and its variant Y65R-MNEI are sweet proteins with potential applications as sweeteners in food industry. Also, they are often used as model systems for folding and aggregation studies.

PubMed: 29288772
DOI: 10.1016/j.bbagen.2017.12.012

実験手法

X-RAY DIFFRACTION (2.05 Å)