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5O6S

UbV.B4R, a dimeric ubiquitin variant binding to BIRC4 RING

Summary for 5O6S
Entry DOI10.2210/pdb5o6s/pdb
DescriptorPolyubiquitin-B (2 entities in total)
Functional Keywordsubiquitin variant, protein binding
Biological sourceHomo sapiens (Human)
Total number of polymer chains6
Total formula weight55454.90
Authors
Gabrielsen, M.,Buetow, L.,Huang, D.T. (deposition date: 2017-06-07, release date: 2017-11-01, Last modification date: 2024-01-17)
Primary citationGabrielsen, M.,Buetow, L.,Nakasone, M.A.,Ahmed, S.F.,Sibbet, G.J.,Smith, B.O.,Zhang, W.,Sidhu, S.S.,Huang, D.T.
A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants.
Mol. Cell, 68:456-470.e10, 2017
Cited by
PubMed: 29053960
DOI: 10.1016/j.molcel.2017.09.027
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation

218500

건을2024-04-17부터공개중

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