5O4U

The flagellin of Pyrococcus furiosus

Summary for 5O4U

• Entry DOI: 10.2210/pdb5o4u/pdb
• EMDB information: 3746
• Descriptor: Flagellin (1 entity in total)
• Functional Keywords: archaellar flagellum glycoprotein helical filament, cell adhesion
• Biological source: Pyrococcus furiosus DSM 3638
• Total number of polymer chains: 16
• Total formula weight: 356533.60

Authors

Daum, B.,Vonck, J. (deposition date: 2017-05-31, release date: 2017-07-05, Last modification date: 2024-05-15)

Primary citation

Daum, B.,Vonck, J.,Bellack, A.,Chaudhury, P.,Reichelt, R.,Albers, S.V.,Rachel, R.,Kuhlbrandt, W.
Structure andin situorganisation of thePyrococcus furiosusarchaellum machinery.
Elife, 6:-, 2017

PubMed Abstract: The archaellum is the macromolecular machinery that Archaea use for propulsion or surface adhesion, enabling them to proliferate and invade new territories. The molecular composition of the archaellum and of the motor that drives it appears to be entirely distinct from that of the functionally equivalent bacterial flagellum and flagellar motor. Yet, the structure of the archaellum machinery is scarcely known. Using combined modes of electron cryo-microscopy (cryoEM), we have solved the structure of the archaellum filament at 4.2 Å resolution and visualise the architecture and organisation of its motor complex . This allows us to build a structural model combining the archaellum and its motor complex, paving the way to a molecular understanding of archaeal swimming motion.

PubMed: 28653905
DOI: 10.7554/eLife.27470

Experimental method

ELECTRON MICROSCOPY (4.2 Å)