5O0B
Crystal structure of Phosphopantetheine adenylyltransferase from Mycobacterium abcessus in complex with 3-Bromo-1H-indazole-5-carboxylic acid (Fragment 2)
Summary for 5O0B
Entry DOI | 10.2210/pdb5o0b/pdb |
Descriptor | Phosphopantetheine adenylyltransferase, 3-bromanyl-1~{H}-indazole-5-carboxylic acid (3 entities in total) |
Functional Keywords | coenzyme a biosynthesis, transferase |
Biological source | Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543) |
Cellular location | Cytoplasm : B1MDL6 |
Total number of polymer chains | 3 |
Total formula weight | 53876.91 |
Authors | Thomas, S.E.,Kim, S.Y.,Mendes, V.,Blaszczyk, M.,Blundell, T.L. (deposition date: 2017-05-16, release date: 2017-06-28, Last modification date: 2024-01-17) |
Primary citation | Thomas, S.E.,Mendes, V.,Kim, S.Y.,Malhotra, S.,Ochoa-Montano, B.,Blaszczyk, M.,Blundell, T.L. Structural Biology and the Design of New Therapeutics: From HIV and Cancer to Mycobacterial Infections: A Paper Dedicated to John Kendrew. J. Mol. Biol., 429:2677-2693, 2017 Cited by PubMed: 28648615DOI: 10.1016/j.jmb.2017.06.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.735 Å) |
Structure validation
Download full validation report