5NZ0
Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with linezolid
Summary for 5NZ0
Entry DOI | 10.2210/pdb5nz0/pdb |
Descriptor | HTH-type transcriptional regulator EthR, N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | ethr, transcription, represor, boosting effect |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 25658.67 |
Authors | Blaszczyk, M.,Mendes, V.,Nikiforov, P.O.,Blundell, T.L. (deposition date: 2017-05-12, release date: 2018-05-30, Last modification date: 2024-01-17) |
Primary citation | Nikiforov, P.O.,Blaszczyk, M.,Mendes, V.,Boshoff, H.I.,Barry, C.E.,Blundell, T.L.,Abell, C. The antibiotics linezolid and sutezolid are ligands for Mycobacterium tuberculosis EthR To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.825 Å) |
Structure validation
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