5NX6

Crystal structure of 1,8-cineole synthase from Streptomyces clavuligerus in complex with 2-fluoroneryl diphosphate

Summary for 5NX6

Entry DOI	10.2210/pdb5nx6/pdb
Descriptor	Pentalenene synthase, (2E)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, MAGNESIUM ION, ... (7 entities in total)
Functional Keywords	terpene synthase, 1, 8-cineole, monoterpenoid, eucalyptol, lyase
Biological source	Streptomyces clavuligerus
Total number of polymer chains	2
Total formula weight	77153.43
Authors	Karuppiah, V.,Leys, D.,Scrutton, N.S. (deposition date: 2017-05-09, release date: 2017-09-20, Last modification date: 2024-01-17)
Primary citation	Karuppiah, V.,Ranaghan, K.E.,Leferink, N.G.H.,Johannissen, L.O.,Shanmugam, M.,Ni Cheallaigh, A.,Bennett, N.J.,Kearsey, L.J.,Takano, E.,Gardiner, J.M.,van der Kamp, M.W.,Hay, S.,Mulholland, A.J.,Leys, D.,Scrutton, N.S. Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase. ACS Catal, 7:6268-6282, 2017 Cited by PubMed: 28966840 DOI: 10.1021/acscatal.7b01924 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.63 Å)

Structure validation