5NWA
Crystal structure of the complex of Tdp1 with duplex DNA
Summary for 5NWA
Entry DOI | 10.2210/pdb5nwa/pdb |
Related | 5NW9 |
Descriptor | Tyrosyl-DNA phosphodiesterase 1, DNA (5'-D(P*AP*AP*TP*GP*CP*GP*CP*AP*TP*TP*A)-3') (2 entities in total) |
Functional Keywords | protein-dna complex, dna repair, nucleosidase, phosphotyrosine diesterase, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 112819.61 |
Authors | Richardson, J.M.,Ruksenaite, E.,Morris, E.R. (deposition date: 2017-05-05, release date: 2018-01-10, Last modification date: 2024-01-17) |
Primary citation | Flett, F.J.,Ruksenaite, E.,Armstrong, L.A.,Bharati, S.,Carloni, R.,Morris, E.R.,Mackay, C.L.,Interthal, H.,Richardson, J.M. Structural basis for DNA 3'-end processing by human tyrosyl-DNA phosphodiesterase 1. Nat Commun, 9:24-24, 2018 Cited by PubMed: 29295983DOI: 10.1038/s41467-017-02530-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
Download full validation report