5NV9

Substrate-bound outward-open state of a Na+-coupled sialic acid symporter reveals a novel Na+-site

5NV9 の概要

• エントリーDOI: 10.2210/pdb5nv9/pdb
• 分子名称: Putative sodium:solute symporter, SODIUM ION, N-acetyl-beta-neuraminic acid, ... (6 entities in total)
• 機能のキーワード: membrane protein, membrane symporter, sialic acid, outward-open, sodium-coupled
• 由来する生物種: Proteus mirabilis (strain HI4320)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 55893.80

構造登録者

Wahlgren, W.Y.,North, R.A.,Dunevall, E.,Paz, A.,Goyal, P.,Bisignano, P.,Grabe, M.,Dobson, R.,Abramson, J.,Ramaswamy, S.,Friemann, R. (登録日: 2017-05-03, 公開日: 2018-04-04, 最終更新日: 2020-07-29)

• 主引用文献: Wahlgren, W.Y.,Dunevall, E.,North, R.A.,Paz, A.,Scalise, M.,Bisignano, P.,Bengtsson-Palme, J.,Goyal, P.,Claesson, E.,Caing-Carlsson, R.,Andersson, R.,Beis, K.,Nilsson, U.J.,Farewell, A.,Pochini, L.,Indiveri, C.,Grabe, M.,Dobson, R.C.J.,Abramson, J.,Ramaswamy, S.,Friemann, R.; Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+site.; Nat Commun, 9:1753-1753, 2018; PubMed: 29717135; DOI: 10.1038/s41467-018-04045-7

実験手法

X-RAY DIFFRACTION (1.95 Å)