5NOR
Structure of cyclophilin A in complex with 3-methylpyridin-2-amine
Summary for 5NOR
| Entry DOI | 10.2210/pdb5nor/pdb |
| Descriptor | Peptidyl-prolyl cis-trans isomerase A, 3-methylpyridin-2-amine (3 entities in total) |
| Functional Keywords | ligand complex, beta barrel, prolyl cis/trans isomerase, cytosolic, isomerase |
| Biological source | Homo sapiens (Human) |
| Cellular location | Cytoplasm : P62937 |
| Total number of polymer chains | 1 |
| Total formula weight | 18252.79 |
| Authors | Georgiou, C.,Mcnae, I.W.,Ioannidis, H.,Julien, M.,Walkinshaw, M.D. (deposition date: 2017-04-13, release date: 2017-07-12, Last modification date: 2024-01-17) |
| Primary citation | Georgiou, C.,McNae, I.,Wear, M.,Ioannidis, H.,Michel, J.,Walkinshaw, M. Pushing the Limits of Detection of Weak Binding Using Fragment-Based Drug Discovery: Identification of New Cyclophilin Binders. J. Mol. Biol., 429:2556-2570, 2017 Cited by PubMed: 28673552DOI: 10.1016/j.jmb.2017.06.016 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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