5NNU

KSHV uracil-DNA glycosylase, product complex with dsDNA exhibiting duplex nucleotide flipping

Summary for 5NNU

• Entry DOI: 10.2210/pdb5nnu/pdb
• Related: 5NN7 5NNH
• Descriptor: DNA containing an abasic site, Uracil-DNA glycosylase, DNA, ... (4 entities in total)
• Functional Keywords: uracil-dna glycosylase, hydrolase
• Biological source: Human herpesvirus 8; More
• Cellular location: Host nucleus : Q76RG8
• Total number of polymer chains: 12
• Total formula weight: 135286.13

Authors

Earl, C.,Bagneris, C.,Barrett, T.,Savva, R. (deposition date: 2017-04-10, release date: 2018-03-21, Last modification date: 2024-01-17)

• Primary citation: Earl, C.,Bagneris, C.,Zeman, K.,Cole, A.,Barrett, T.,Savva, R.; A structurally conserved motif in gamma-herpesvirus uracil-DNA glycosylases elicits duplex nucleotide-flipping.; Nucleic Acids Res., 46:4286-4300, 2018; PubMed: 29596604; DOI: 10.1093/nar/gky217

Experimental method

X-RAY DIFFRACTION (2.97 Å)