5NFB

Structure of Galectin-3 CRD in complex with compound 4

5NFB の概要

• エントリーDOI: 10.2210/pdb5nfb/pdb
• 関連するPDBエントリー: 5NF7 5NF9 5NFA
• 分子名称: Galectin-3, ~{N}-[(2~{R},3~{R},4~{R},5~{S},6~{R})-2-acetamido-6-(hydroxymethyl)-5-[(2~{S},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-4-[(3-methoxyphenyl)methoxy]-3,5-bis(oxidanyl)oxan-2-yl]oxy-4-oxidanyl-oxan-3-yl]-3-methoxy-benzamide (3 entities in total)
• 機能のキーワード: galectin-3 crd, cation-pi interactions, sugar binding protein
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cytoplasm: P17931
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20572.08

構造登録者

Ronin, C.,Atmanene, C.,Gautier, F.M.,Djedaini Pilard, F.,Teletchea, S.,Ciesielski, F.,Vivat Hannah, V.,Grandjean, C. (登録日: 2017-03-13, 公開日: 2017-06-21, 最終更新日: 2024-01-17)

• 主引用文献: Atmanene, C.,Ronin, C.,Teletchea, S.,Gautier, F.M.,Djedaini-Pilard, F.,Ciesielski, F.,Vivat, V.,Grandjean, C.; Biophysical and structural characterization of mono/di-arylated lactosamine derivatives interaction with human galectin-3.; Biochem. Biophys. Res. Commun., 489:281-286, 2017; PubMed: 28554839; DOI: 10.1016/j.bbrc.2017.05.150

実験手法

X-RAY DIFFRACTION (1.59 Å)