5NE2

L2 class A serine-beta-lactamase

Summary for 5NE2

• Entry DOI: 10.2210/pdb5ne2/pdb
• Descriptor: Beta-lactamase, D-GLUTAMIC ACID (3 entities in total)
• Functional Keywords: beta-lactamase, carbapenemase, hydrolase
• Biological source: Stenotrophomonas maltophilia (Pseudomonas maltophilia)
• Total number of polymer chains: 2
• Total formula weight: 58930.71

Authors

Hinchliffe, P.,Calvopina, K.,Spencer, J. (deposition date: 2017-03-09, release date: 2017-09-13, Last modification date: 2024-01-17)

• Primary citation: Calvopina, K.,Hinchliffe, P.,Brem, J.,Heesom, K.J.,Johnson, S.,Cain, R.,Lohans, C.T.,Fishwick, C.W.G.,Schofield, C.J.,Spencer, J.,Avison, M.B.; Structural/mechanistic insights into the efficacy of nonclassical beta-lactamase inhibitors against extensively drug resistant Stenotrophomonas maltophilia clinical isolates.; Mol. Microbiol., 106:492-504, 2017; PubMed: 28876489; DOI: 10.1111/mmi.13831

Experimental method

X-RAY DIFFRACTION (1.19 Å)