5NDJ

Crystal structure of aminoglycoside TC007 in complex with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA (soaking)

これはPDB形式変換不可エントリーです。

5NDJ の概要

• エントリーDOI: 10.2210/pdb5ndj/pdb
• 分子名称: 16S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L24, ... (56 entities in total)
• 機能のキーワード: translation, ribosome, 30s, 50s, 70s, trna, mrna, bacteria, rna-protein complex, inhibitor, antibiotic, aminoglycoside
• 由来する生物種: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579); 詳細
• タンパク質・核酸の鎖数: 108
• 化学式量合計: 4529172.80

構造登録者

Prokhorova, I.,Djumagulov, M.,Urzhumtsev, A.,Yusupov, M.,Yusupova, G. (登録日: 2017-03-08, 公開日: 2018-05-02)

• 主引用文献: Prokhorova, I.,Altman, R.B.,Djumagulov, M.,Shrestha, J.P.,Urzhumtsev, A.,Ferguson, A.,Chang, C.T.,Yusupov, M.,Blanchard, S.C.,Yusupova, G.; Aminoglycoside interactions and impacts on the eukaryotic ribosome.; Proc. Natl. Acad. Sci. U.S.A., 114:E10899-E10908, 2017; PubMed: 29208708; DOI: 10.1073/pnas.1715501114

実験手法

X-RAY DIFFRACTION (3.15 Å)