5NBW

Crystal structure of the Fab fragment 22F12 in complex with 3-hydroxybenzo[a]pyrene

Summary for 5NBW

• Entry DOI: 10.2210/pdb5nbw/pdb
• Descriptor: Fab 22F12 (L,H), Fab 22F12 (A,B), benzo[a]pyren-3-ol, ... (4 entities in total)
• Functional Keywords: antibody, benzo[a]pyrene, fab fragment, hapten, immune system
• Biological source: Mus musculus (House Mouse); More
• Total number of polymer chains: 4
• Total formula weight: 96609.25

Authors

Skerra, A.,Eichinger, A. (deposition date: 2017-03-02, release date: 2017-06-28, Last modification date: 2024-01-17)

• Primary citation: Eichinger, A.,Neumaier, I.,Pschenitza, M.,Niessner, R.,Knopp, D.,Skerra, A.; Tight Molecular Recognition of Benzo[a]pyrene by a High-Affinity Antibody.; Angew. Chem. Int. Ed. Engl., 56:10592-10597, 2017; PubMed: 28603847; DOI: 10.1002/anie.201703893

Experimental method

X-RAY DIFFRACTION (2.4 Å)